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- J. Mol. Cat. B: Enz - Increase of stability of oleate hydratase by appropriate immobilization technique and conditions - A. Hiseni and I. Arends
- Process Biochem. - Optimizing the chloroperoxidase–glucose oxidase system: the effect of glucose oxidase on activity and enantioselectivity - P.C. Pereira, I.W.C.E. Arends and R.A. Sheldon
- ChemComm - Al(OH)3 facilitated synthesis of water-soluble, magnetic, radiolabelled and fluorescent hydroxyapatite nanoparticles - W. Zhang, K. Djanashvili
- Adv. Synth. and Cat. - Complete enzymatic oxidation of methanol to carbon dioxide: towards more eco-efficient regeneration systems for reduced nicotinamide cofactors - S. Kara J. Schrittwiese, S. Garguilo, F. Hollmann
- ACS Catal. - Nonenzymatic regeneration of styrene monooxygenase for catalysis - C.E. Paul and F. Hollmann
- J. Mol. Cat. B: Enz. - Medium and reaction engineering for the establishment of a chemo-enzymatic dynamic kinetic resolution of rac-benzoin in batch and continuous mode - U. Hanefeld
- J. Mol. Cat. B: Enz. - Enzymatic cascade synthesis of (S)-2-hydroxycarboxylic amides and acids: cascade reactions employing a hydroxynitrile lyase, nitrile-converting enzymes and an amidase - F. van Rantwijk
De section Biocatalysis brings together scientists in the area of biocatalysis, enzymology, organic chemistry and molecular imaging.
Our research on fundamental understanding of enzymes and the application thereof in organic chemistry, forms the basis for the application of enzymes into industrial processes. Green Chemistry is one of our leitmotivs.
Our research projects range from fundamental insight into enzymatic principles, to engineering of enzymes and integration of these enzymes into novel synthetic procedures. The combination of biocatalysts and chemocatalysts in one-pot is one of the key expertises in the group. In addition, the search for novel enzymes and novel activities through a combination of smart concise library design, screening with generic assays and bioinformatics modelling, denoted as molecular enzyme evolution, is a growing area. In particular for the future of biomass utilization, novel enzymes are expected to make a major contribution as catalysts.
In the area of molecular imaging, nanoprobes are designed and synthesized for imaging and therapy applications.
The infrastructure of the group consists of state-of-the-art biochemistry, molecular biology, analytical (GC and HPLC) and organic chemistry facilities. The university NMR facility is under the administration of the section.
As a section we contribute to the education of BSc and MSc students in the area of Life Science and Technology (LST) and Molecular Science and Technology (MST). For openings on BSc and MSc research projects students are referred to the student projects page. In addition, the annual Advanced Course on Biocatalysis is organized by the section already for many years under auspice of BSDL.
- Enzymes as Catalysts for industrial Biotechnology
- Chemo-enzymatic cascade reactions
- Application of enzymes in Organic Chemistry
- Biocatalytic pathways for redox transformations
- Molecular enzyme evolution
- Ultrafast Kinetic Techniques to Study Enzyme Reactions
- Generic enzyme assays
- (Nano)probes for bio-imaging and therapy
The section Biocatalysis is a member of the dutch NIOK research school on catalysis.