Prof.dr. J.T. (Jack) Pronk

Biography

• 1999 - present
  Full professor and Group leader Industrial Microbiology Group, Department of Biotechnology, Faculty of Applied Sciences, Delft University of Technology
• 1991 - 1999
  Assistant professor Microbiology group, Department of Biotechnology, Faculty of Applied Sciences, Delft University of Technology
• 1991
  PhD research 'Physiology of the acidophilic thiobacilli'. Microbiology group, Department of Biotechnology, Faculty of Applied Sciences, Delft University of Technology
• 1986
  MSc Plant Molecular Biology (cum laude), Leiden University, The Netherlands

Scientific director NWO-NGI Center of Excellence 'Kluyver Centre for Genomics of Industrial Fermentation', since 2003

Research interests

• Quantitative physiology and controlled cultivation of yeasts and fungi
• Metabolic engineering and synthetic biology
• Genomics and systems biology

Teaching activities

• Delft-Leiden BSc and MSc programmes in Life Science and Technology. Teacher in courses on biofarmaceutical technology, biotechnology, microbial physiology and fermentation technology. Coordinator of MSc profile 'Cell Factory', chairman of examination committee.
• International Advanced Courses: microbial physiology and fermentation technology, applied genomics of industrial fermentation
• Supervised 12 PhD’s until 2008

Key publications

• Tai, S.L., Daran-Lapujade, P., Luttik, M.A.H., Walsh, M.C., Diderich, J.A., Krijger, G.C., van Gulik, W.M., Pronk, J.T. and Daran, J.M. (2007) Control of the glycolytic flux in Saccharomyces cerevisiae grown at low temperature: a multi-level analysis in anaerobic chemostat cultures. Journal of Biological Chemistry 282: 10243-10251.
• Kuyper, M., Toirkens, M.J., Diderich, J.A., Winkler, A.A., Van Dijken, J.P. and Pronk, J.T. (2005) Evolutionary engineering of mixed-sugar utilization by a xylose-fermenting Saccharomyces cerevisiae strain. FEMS Yeast Research 5: 925-934.
• Boer, V.M., de Winde, J.H., Pronk, J.T. and Piper, M.D.W. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. Journal of Biological Chemistry 278: 3265-3274.
• Luttik, M.A.H., Overkamp, K.M., Kötter, P., de Vries, S., van Dijken, J.P. and Pronk, J.T. (1998) The Saccharomyces cerevisiae NDE1 and NDE2 genes encode separate mitochondrial NADH dehydrogenases catalyzing the oxidation of cytosolic NADH. Journal of Biological Chemistry 273: 24529-24534.
• Flikweert, M.T., van der Zanden, L., Janssen, W.M.Th.M., Steensma, H.Y., van Dijken, J.P. and Pronk, J.T. (1996) Pyruvate decarboxylase: an indispensable enzyme for growth of Saccharomyces cerevisiae on glucose. Yeast 12: 247-257.

Secondary employment

• Advisor gist- en schimmelfysiologie/genomics - DSM Life Sciences.

Personal website

Website/publications Jack Pronk (to follow)